Differential TAM receptor–ligand–phospholipid interactions delimit differential TAM bioactivities

The TAM receptor tyrosine kinases Tyro3, Axl, and Mer regulate key features of cellular physiology, yet the differential activities of the TAM ligands Gas6 and Protein S are poorly understood. We have used biochemical and genetic analyses to delineate the rules for TAM receptor–ligand engagement and...

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Detalles Bibliográficos
Autores principales: Lew, Erin D, Oh, Jennifer, Burrola, Patrick G, Lax, Irit, Zagórska, Anna, Través, Paqui G, Schlessinger, Joseph, Lemke, Greg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2014
Materias:
Biochemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4206827/
https://www.ncbi.nlm.nih.gov/pubmed/25265470
http://dx.doi.org/10.7554/eLife.03385

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4206827/
https://www.ncbi.nlm.nih.gov/pubmed/25265470
http://dx.doi.org/10.7554/eLife.03385

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