Cargando…
Differential TAM receptor–ligand–phospholipid interactions delimit differential TAM bioactivities
The TAM receptor tyrosine kinases Tyro3, Axl, and Mer regulate key features of cellular physiology, yet the differential activities of the TAM ligands Gas6 and Protein S are poorly understood. We have used biochemical and genetic analyses to delineate the rules for TAM receptor–ligand engagement and...
Autores principales: | Lew, Erin D, Oh, Jennifer, Burrola, Patrick G, Lax, Irit, Zagórska, Anna, Través, Paqui G, Schlessinger, Joseph, Lemke, Greg |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4206827/ https://www.ncbi.nlm.nih.gov/pubmed/25265470 http://dx.doi.org/10.7554/eLife.03385 |
Ejemplares similares
-
Diversification of TAM receptor function
por: Zagórska, Anna, et al.
Publicado: (2014) -
TAM receptors regulate multiple features of microglial physiology
por: Fourgeaud, Lawrence, et al.
Publicado: (2016) -
Differential regulation of hepatic physiology and injury by the TAM receptors Axl and Mer
por: Zagórska, Anna, et al.
Publicado: (2020) -
Regulation of brain endothelial cell physiology by the TAM receptor tyrosine kinase Mer
por: Happonen, Kaisa E., et al.
Publicado: (2023) -
Microglia use TAM receptors to detect and engulf amyloid beta plaques
por: Huang, Youtong, et al.
Publicado: (2021)