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Disturbances of Tryptophan Metabolism and Risk of Depression in HCV Patients Treated with IFN-Alpha

Depression is a common side-effect of interferon (IFN)-alpha treatment of hepatitis C virus (HCV) infection and melanoma. Disturbances of tryptophan (TRP) metabolism might contribute to development of IFN-alpha–associated depression due to IFN-alpha-induced activation of indoleamine 2,3-dioxygenase...

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Detalles Bibliográficos
Autores principales: Oxenkrug, GF, Turski, WA, Zgrajka, W, Weinstock, JV, Ruthazer, R, Summergrad, P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4206908/
https://www.ncbi.nlm.nih.gov/pubmed/25346938
http://dx.doi.org/10.4172/2332-0877.1000131