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From molecular signatures to predictive biomarkers: modeling disease pathophysiology and drug mechanism of action

Omics profiling significantly expanded the molecular landscape describing clinical phenotypes. Association analysis resulted in first diagnostic and prognostic biomarker signatures entering clinical utility. However, utilizing Omics for deepening our understanding of disease pathophysiology, and fur...

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Detalles Bibliográficos
Autores principales: Heinzel, Andreas, Perco, Paul, Mayer, Gert, Oberbauer, Rainer, Lukas, Arno, Mayer, Bernd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4207010/
https://www.ncbi.nlm.nih.gov/pubmed/25364744
http://dx.doi.org/10.3389/fcell.2014.00037