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To develop with or without the prion protein

The deletion of the cellular form of the prion protein (PrP(C)) in mouse, goat, and cattle has no drastic phenotypic consequence. This stands in apparent contradiction with PrP(C) quasi-ubiquitous expression and conserved primary and tertiary structures in mammals, and its pivotal role in neurodegen...

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Detalles Bibliográficos
Autores principales:	Halliez, Sophie, Passet, Bruno, Martin-Lannerée, Séverine, Hernandez-Rapp, Julia, Laude, Hubert, Mouillet-Richard, Sophie, Vilotte, Jean-Luc, Béringue, Vincent
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2014
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4207017/ https://www.ncbi.nlm.nih.gov/pubmed/25364763 http://dx.doi.org/10.3389/fcell.2014.00058

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