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Profiling and targeting HER2-positive breast cancer using trastuzumab emtansine

PURPOSE: This article reviews the mechanism of action of trastuzumab emtansine (T-DM1), existing clinical data relating to its use for human growth factor receptor 2 (HER2)-positive breast cancer, potential pathways of resistance, and ongoing studies evaluating this novel agent. BACKGROUND: The deve...

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Detalles Bibliográficos
Autores principales:	Sadeghi, Saeed, Olevsky, Olga, Hurvitz, Sara A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2014
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4207068/ https://www.ncbi.nlm.nih.gov/pubmed/25378946 http://dx.doi.org/10.2147/PGPM.S47524

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