Cyclic Adenosine 5′-Diphosphate Ribose Analogs without a “Southern” Ribose Inhibit ADP-ribosyl Cyclase–Hydrolase CD38

[Image: see text] Cyclic adenosine 5′-diphosphate ribose (cADPR) analogs based on the cyclic inosine 5′-diphosphate ribose (cIDPR) template were synthesized by recently developed stereo- and regioselective N1-ribosylation. Replacing the base N9-ribose with a butyl chain generates inhibitors of cADPR...

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Detalles Bibliográficos
Autores principales: Swarbrick, Joanna M., Graeff, Richard, Zhang, Hongmin, Thomas, Mark P., Hao, Quan, Potter, Barry V. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4207131/
https://www.ncbi.nlm.nih.gov/pubmed/25226087
http://dx.doi.org/10.1021/jm501037u

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4207131/
https://www.ncbi.nlm.nih.gov/pubmed/25226087
http://dx.doi.org/10.1021/jm501037u

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