Experimental Design-Based Response Surface Methodology Optimization for Synthesis of β-Mercapto Carbonyl Derivatives as Antimycobacterial Drugs Catalyzed by Calcium Pyrophosphate

A simple protocol for the efficient preparation of β-mercapto carbonyl derivatives as antimycobacterial drugs has been achieved via Thia-Michael reaction between chalcones derivatives and thiols in the presence of calcium pyrophosphate as a heterogeneous catalyst under mild reaction conditions. The...

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Detalles Bibliográficos
Autores principales: Abrouki, Younes, Anouzla, Abdelkader, Loukili, Hayat, Bennazha, Jamal, Lotfi, Rabiaâ, Rayadh, Ahmed, Bahlaoui, My Abdellah, Sebti, Saïd, Zakarya, Driss, Zahouily, Mohamed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4207383/
https://www.ncbi.nlm.nih.gov/pubmed/25383218
http://dx.doi.org/10.1155/2014/586437

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