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Blood and Islet Phenotypes Indicate Immunological Heterogeneity in Type 1 Diabetes

Studies in type 1 diabetes indicate potential disease heterogeneity, notably in the rate of β-cell loss, responsiveness to immunotherapies, and, in limited studies, islet pathology. We sought evidence for different immunological phenotypes using two approaches. First, we defined blood autoimmune res...

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Detalles Bibliográficos
Autores principales: Arif, Sefina, Leete, Pia, Nguyen, Vy, Marks, Katherine, Nor, Nurhanani Mohamed, Estorninho, Megan, Kronenberg-Versteeg, Deborah, Bingley, Polly J., Todd, John A., Guy, Catherine, Dunger, David B., Powrie, Jake, Willcox, Abby, Foulis, Alan K., Richardson, Sarah J., de Rinaldis, Emanuele, Morgan, Noel G., Lorenc, Anna, Peakman, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4207393/
https://www.ncbi.nlm.nih.gov/pubmed/24939426
http://dx.doi.org/10.2337/db14-0365