The Development of Models Based on Linear and Nonlinear Multivariate Methods to Predict ADME/PK Properties Using Physicochemical Properties of Kinase, Protease Inhibitors, and GPCR Antagonists

Oral bioavailability of a drug compound is the significant property for potential drug candidates. Measuring this property can be costly and time-consuming. Quantitative structure-property relationships (QSPRs) are used to estimate the percentage of oral bioavailability, and they are an attractive a...

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Detalles Bibliográficos
Autores principales: Bakasta, Deepu, Shambhu, M. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4207418/
https://www.ncbi.nlm.nih.gov/pubmed/25374691
http://dx.doi.org/10.1155/2013/495134

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4207418/
https://www.ncbi.nlm.nih.gov/pubmed/25374691
http://dx.doi.org/10.1155/2013/495134

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