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Improving B-cell epitope prediction and its application to global antibody-antigen docking

Motivation: Antibodies are currently the most important class of biopharmaceuticals. Development of such antibody-based drugs depends on costly and time-consuming screening campaigns. Computational techniques such as antibody–antigen docking hold the potential to facilitate the screening process by...

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Detalles Bibliográficos
Autores principales: Krawczyk, Konrad, Liu, Xiaofeng, Baker, Terry, Shi, Jiye, Deane, Charlotte M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4207425/
https://www.ncbi.nlm.nih.gov/pubmed/24753488
http://dx.doi.org/10.1093/bioinformatics/btu190