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Synthesis, Structure–Activity Relationship Studies, and Antibacterial Evaluation of 4-Chromanones and Chalcones, as Well as Olympicin A and Derivatives

[Image: see text] On the basis of recently reported abyssinone II and olympicin A, a series of chemically modified flavonoid phytochemicals were synthesized and evaluated against Mycobacterium tuberculosis and a panel of Gram-positive and -negative bacterial pathogens. Some of the synthesized compou...

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Detalles Bibliográficos
Autores principales: Feng, Li, Maddox, Marcus M., Alam, Md. Zahidul, Tsutsumi, Lissa S., Narula, Gagandeep, Bruhn, David F., Wu, Xiaoqian, Sandhaus, Shayna, Lee, Robin B., Simmons, Charles J., Tse-Dinh, Yuk-Ching, Hurdle, Julian G., Lee, Richard E., Sun, Dianqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4207537/
https://www.ncbi.nlm.nih.gov/pubmed/25238443
http://dx.doi.org/10.1021/jm500853v