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More than 9 years of continuous trastuzumab treatment in metastatic breast cancer without cardiac toxicity: a case report and literature review

The main concern of long-term use of trastuzumab remains its association with potential cardiac side effects. Although these side effects are real, they are probably overemphasized. We report the case of a woman with metastatic breast cancer, who is currently in complete remission, and who received...

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Detalles Bibliográficos
Autores principales: Badulescu, Florin, Badulescu, Adriana, Paul, Doru, Popescu, Carmen Florina, Florescu, Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4207577/
https://www.ncbi.nlm.nih.gov/pubmed/25378932
http://dx.doi.org/10.2147/OTT.S69343
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author Badulescu, Florin
Badulescu, Adriana
Paul, Doru
Popescu, Carmen Florina
Florescu, Cristina
author_facet Badulescu, Florin
Badulescu, Adriana
Paul, Doru
Popescu, Carmen Florina
Florescu, Cristina
author_sort Badulescu, Florin
collection PubMed
description The main concern of long-term use of trastuzumab remains its association with potential cardiac side effects. Although these side effects are real, they are probably overemphasized. We report the case of a woman with metastatic breast cancer, who is currently in complete remission, and who received trastuzumab continuously for more than 9 years, without any significant cardiac toxicity.
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spelling pubmed-42075772014-11-06 More than 9 years of continuous trastuzumab treatment in metastatic breast cancer without cardiac toxicity: a case report and literature review Badulescu, Florin Badulescu, Adriana Paul, Doru Popescu, Carmen Florina Florescu, Cristina Onco Targets Ther Case Report The main concern of long-term use of trastuzumab remains its association with potential cardiac side effects. Although these side effects are real, they are probably overemphasized. We report the case of a woman with metastatic breast cancer, who is currently in complete remission, and who received trastuzumab continuously for more than 9 years, without any significant cardiac toxicity. Dove Medical Press 2014-10-17 /pmc/articles/PMC4207577/ /pubmed/25378932 http://dx.doi.org/10.2147/OTT.S69343 Text en © 2014 Badulescu et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.
spellingShingle Case Report
Badulescu, Florin
Badulescu, Adriana
Paul, Doru
Popescu, Carmen Florina
Florescu, Cristina
More than 9 years of continuous trastuzumab treatment in metastatic breast cancer without cardiac toxicity: a case report and literature review
title More than 9 years of continuous trastuzumab treatment in metastatic breast cancer without cardiac toxicity: a case report and literature review
title_full More than 9 years of continuous trastuzumab treatment in metastatic breast cancer without cardiac toxicity: a case report and literature review
title_fullStr More than 9 years of continuous trastuzumab treatment in metastatic breast cancer without cardiac toxicity: a case report and literature review
title_full_unstemmed More than 9 years of continuous trastuzumab treatment in metastatic breast cancer without cardiac toxicity: a case report and literature review
title_short More than 9 years of continuous trastuzumab treatment in metastatic breast cancer without cardiac toxicity: a case report and literature review
title_sort more than 9 years of continuous trastuzumab treatment in metastatic breast cancer without cardiac toxicity: a case report and literature review
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4207577/
https://www.ncbi.nlm.nih.gov/pubmed/25378932
http://dx.doi.org/10.2147/OTT.S69343
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