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Mucuna pruriens (Velvet bean) Rescues Motor, Olfactory, Mitochondrial and Synaptic Impairment in PINK1(B9) Drosophila melanogaster Genetic Model of Parkinson’s Disease

The fruit fly Drosophila melanogaster (Dm) mutant for PTEN-induced putative kinase 1 (PINK1(B9)) gene is a powerful tool to investigate physiopathology of Parkinson's disease (PD). Using PINK1(B9) mutant Dm we sought to explore the effects of Mucuna pruriens methanolic extract (Mpe), a L-Dopa-c...

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Detalles Bibliográficos
Autores principales:	Poddighe, Simone, De Rose, Francescaelena, Marotta, Roberto, Ruffilli, Roberta, Fanti, Maura, Secci, Pietro Paolo, Mostallino, Maria Cristina, Setzu, Maria Dolores, Zuncheddu, Maria Antonietta, Collu, Ignazio, Solla, Paolo, Marrosu, Francesco, Kasture, Sanjay, Acquas, Elio, Liscia, Anna
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4207759/ https://www.ncbi.nlm.nih.gov/pubmed/25340511 http://dx.doi.org/10.1371/journal.pone.0110802

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