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The Tacrolimus Metabolism Rate Influences Renal Function after Kidney Transplantation

The effective calcineurin inhibitor (CNI) tacrolimus (Tac) is an integral part of the standard immunosuppressive regimen after renal transplantation (RTx). However, as a potent CNI it has nephrotoxic potential leading to impaired renal function in some cases. Therefore, it is of high clinical impact...

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Detalles Bibliográficos
Autores principales: Thölking, Gerold, Fortmann, Christian, Koch, Raphael, Gerth, Hans Ulrich, Pabst, Dirk, Pavenstädt, Hermann, Kabar, Iyad, Hüsing, Anna, Wolters, Heiner, Reuter, Stefan, Suwelack, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4207775/
https://www.ncbi.nlm.nih.gov/pubmed/25340655
http://dx.doi.org/10.1371/journal.pone.0111128

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