The Inhibition of N-Glycosylation of Glycoprotein 130 Molecule Abolishes STAT3 Activation by IL-6 Family Cytokines in Cultured Cardiac Myocytes

Interleukin-6 (IL-6) family cytokines play important roles in cardioprotection against pathological stresses. IL-6 cytokines bind to their specific receptors and activate glycoprotein 130 (gp130), a common receptor, followed by further activation of STAT3 and extracellular signal-regulated kinase (E...

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Detalles Bibliográficos
Autores principales: Matsuo, Reo, Morihara, Hirofumi, Mohri, Tomomi, Murasawa, Shiho, Takewaki, Kana, Nakayama, Hiroyuki, Maeda, Makiko, Fujio, Yasushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4207791/
https://www.ncbi.nlm.nih.gov/pubmed/25340554
http://dx.doi.org/10.1371/journal.pone.0111097

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