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Geriatric Fever Score: A New Decision Rule for Geriatric Care

BACKGROUND: Evaluating geriatric patients with fever is time-consuming and challenging. We investigated independent mortality predictors of geriatric patients with fever and developed a prediction rule for emergency care, critical care, and geriatric care physicians to classify patients into mortali...

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Autores principales: Chung, Min-Hsien, Huang, Chien-Cheng, Vong, Si-Chon, Yang, Tzu-Meng, Chen, Kuo-Tai, Lin, Hung-Jung, Chen, Jiann-Hwa, Su, Shih-Bin, Guo, How-Ran, Hsu, Chien-Chin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4207798/
https://www.ncbi.nlm.nih.gov/pubmed/25340811
http://dx.doi.org/10.1371/journal.pone.0110927
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author Chung, Min-Hsien
Huang, Chien-Cheng
Vong, Si-Chon
Yang, Tzu-Meng
Chen, Kuo-Tai
Lin, Hung-Jung
Chen, Jiann-Hwa
Su, Shih-Bin
Guo, How-Ran
Hsu, Chien-Chin
author_facet Chung, Min-Hsien
Huang, Chien-Cheng
Vong, Si-Chon
Yang, Tzu-Meng
Chen, Kuo-Tai
Lin, Hung-Jung
Chen, Jiann-Hwa
Su, Shih-Bin
Guo, How-Ran
Hsu, Chien-Chin
author_sort Chung, Min-Hsien
collection PubMed
description BACKGROUND: Evaluating geriatric patients with fever is time-consuming and challenging. We investigated independent mortality predictors of geriatric patients with fever and developed a prediction rule for emergency care, critical care, and geriatric care physicians to classify patients into mortality risk and disposition groups. MATERIALS AND METHODS: Consecutive geriatric patients (≥65 years old) visiting the emergency department (ED) of a university-affiliated medical center between June 1 and July 21, 2010, were enrolled when they met the criteria of fever: a tympanic temperature ≥37.2°C or a baseline temperature elevated ≥1.3°C. Thirty-day mortality was the primary endpoint. Internal validation with bootstrap re-sampling was done. RESULTS: Three hundred thirty geriatric patients were enrolled. We found three independent mortality predictors: Leukocytosis (WBC >12,000 cells/mm(3)), Severe coma (GCS ≤ 8), and Thrombocytopenia (platelets <150 10(3)/mm(3)) (LST). After assigning weights to each predictor, we developed a Geriatric Fever Score that stratifies patients into two mortality-risk and disposition groups: low (4.0%) (95% CI: 2.3–6.9%): a general ward or treatment in the ED then discharge and high (30.3%) (95% CI: 17.4–47.3%): consider the intensive care unit. The area under the curve for the rule was 0.73. CONCLUSIONS: We found that the Geriatric Fever Score is a simple and rapid rule for predicting 30-day mortality and classifying mortality risk and disposition in geriatric patients with fever, although external validation should be performed to confirm its usefulness in other clinical settings. It might help preserve medical resources for patients in greater need.
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spelling pubmed-42077982014-10-27 Geriatric Fever Score: A New Decision Rule for Geriatric Care Chung, Min-Hsien Huang, Chien-Cheng Vong, Si-Chon Yang, Tzu-Meng Chen, Kuo-Tai Lin, Hung-Jung Chen, Jiann-Hwa Su, Shih-Bin Guo, How-Ran Hsu, Chien-Chin PLoS One Research Article BACKGROUND: Evaluating geriatric patients with fever is time-consuming and challenging. We investigated independent mortality predictors of geriatric patients with fever and developed a prediction rule for emergency care, critical care, and geriatric care physicians to classify patients into mortality risk and disposition groups. MATERIALS AND METHODS: Consecutive geriatric patients (≥65 years old) visiting the emergency department (ED) of a university-affiliated medical center between June 1 and July 21, 2010, were enrolled when they met the criteria of fever: a tympanic temperature ≥37.2°C or a baseline temperature elevated ≥1.3°C. Thirty-day mortality was the primary endpoint. Internal validation with bootstrap re-sampling was done. RESULTS: Three hundred thirty geriatric patients were enrolled. We found three independent mortality predictors: Leukocytosis (WBC >12,000 cells/mm(3)), Severe coma (GCS ≤ 8), and Thrombocytopenia (platelets <150 10(3)/mm(3)) (LST). After assigning weights to each predictor, we developed a Geriatric Fever Score that stratifies patients into two mortality-risk and disposition groups: low (4.0%) (95% CI: 2.3–6.9%): a general ward or treatment in the ED then discharge and high (30.3%) (95% CI: 17.4–47.3%): consider the intensive care unit. The area under the curve for the rule was 0.73. CONCLUSIONS: We found that the Geriatric Fever Score is a simple and rapid rule for predicting 30-day mortality and classifying mortality risk and disposition in geriatric patients with fever, although external validation should be performed to confirm its usefulness in other clinical settings. It might help preserve medical resources for patients in greater need. Public Library of Science 2014-10-23 /pmc/articles/PMC4207798/ /pubmed/25340811 http://dx.doi.org/10.1371/journal.pone.0110927 Text en © 2014 Chung et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Research Article
Chung, Min-Hsien
Huang, Chien-Cheng
Vong, Si-Chon
Yang, Tzu-Meng
Chen, Kuo-Tai
Lin, Hung-Jung
Chen, Jiann-Hwa
Su, Shih-Bin
Guo, How-Ran
Hsu, Chien-Chin
Geriatric Fever Score: A New Decision Rule for Geriatric Care
title Geriatric Fever Score: A New Decision Rule for Geriatric Care
title_full Geriatric Fever Score: A New Decision Rule for Geriatric Care
title_fullStr Geriatric Fever Score: A New Decision Rule for Geriatric Care
title_full_unstemmed Geriatric Fever Score: A New Decision Rule for Geriatric Care
title_short Geriatric Fever Score: A New Decision Rule for Geriatric Care
title_sort geriatric fever score: a new decision rule for geriatric care
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4207798/
https://www.ncbi.nlm.nih.gov/pubmed/25340811
http://dx.doi.org/10.1371/journal.pone.0110927
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