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Influence of the Hinge Region and Its Adjacent Domains on Binding and Signaling Patterns of the Thyrotropin and Follitropin Receptor

Glycoprotein hormone receptors (GPHR) have a large extracellular domain (ECD) divided into the leucine rich repeat (LRR) domain for binding of the glycoprotein hormones and the hinge region (HinR), which connects the LRR domain with the transmembrane domain (TMD). Understanding of the activation mec...

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Detalles Bibliográficos
Autores principales:	Schaarschmidt, Jörg, Huth, Sandra, Meier, René, Paschke, Ralf, Jaeschke, Holger
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4207802/ https://www.ncbi.nlm.nih.gov/pubmed/25340405 http://dx.doi.org/10.1371/journal.pone.0111570

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