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Understanding the complex-I-ty of metformin action: limiting mitochondrial respiration to improve cancer therapy
Metformin has been a first-line treatment for type II diabetes mellitus for decades and is the most widely prescribed antidiabetic drug. Retrospective studies have found that metformin treatment is associated with both reduced cancer diagnoses and cancer-related deaths. Despite the prevalence of met...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4207883/ https://www.ncbi.nlm.nih.gov/pubmed/25347702 http://dx.doi.org/10.1186/s12915-014-0082-4 |