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Elevated Circulating Sclerostin Concentrations in Individuals With High Bone Mass, With and Without LRP5 Mutations

CONTEXT: The role and importance of circulating sclerostin is poorly understood. High bone mass (HBM) caused by activating LRP5 mutations has been reported to be associated with increased plasma sclerostin concentrations; whether the same applies to HBM due to other causes is unknown. OBJECTIVE: Our...

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Detalles Bibliográficos
Autores principales:	Gregson, Celia L., Poole, Kenneth E. S., McCloskey, Eugene V., Duncan, Emma L., Rittweger, Jörn, Fraser, William D., Smith, George Davey, Tobias, Jonathan H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Endocrine Society 2014
Materias:	Endocrine Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4207929/ https://www.ncbi.nlm.nih.gov/pubmed/24606091 http://dx.doi.org/10.1210/jc.2013-3958

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