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Manipulation of PBF/PTTG1IP Phosphorylation Status; a Potential New Therapeutic Strategy for Improving Radioiodine Uptake in Thyroid and Other Tumors

CONTEXT: The clinical effectiveness of ablative radioiodine treatment of thyroid tumors is limited by the availability of the sodium iodide symporter (NIS) at the plasma membrane (PM) for uptake of (131)I. A significant proportion of well-differentiated thyroid tumors are unable to concentrate suffi...

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Detalles Bibliográficos
Autores principales:	Smith, V. E., Sharma, N., Watkins, R. J., Read, M. L., Ryan, G. A., Kwan, P. P., Martin, A., Watkinson, J. C., Boelaert, K., Franklyn, J. A., McCabe, C. J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Endocrine Society 2013
Materias:	Endocrine Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4207948/ https://www.ncbi.nlm.nih.gov/pubmed/23678037 http://dx.doi.org/10.1210/jc.2012-3640

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