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Elevated Periimplantation Uterine Natural Killer Cell Density in Human Endometrium Is Associated With Impaired Corticosteroid Signaling in Decidualizing Stromal Cells
BACKGROUND: Decidualizing human endometrial stromal cells (HESCs) profoundly up-regulate 11β-hydroxysteroid dehydrogenase type 1 (11βHSD1), the enzyme that converts inert cortisone to active cortisol. We postulated that the induction of a cortisol gradient upon decidualization of the periimplantatio...
Autores principales: | Kuroda, Keiji, Venkatakrishnan, Radha, James, Sean, Šućurović, Sandra, Mulac-Jericevic, Biserka, Lucas, Emma S., Takeda, Satoru, Shmygol, Anatoly, Brosens, Jan J., Quenby, Siobhan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Endocrine Society
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4207949/ https://www.ncbi.nlm.nih.gov/pubmed/24025400 http://dx.doi.org/10.1210/jc.2013-1977 |
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