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Whole-cell biotransformation systems for reduction of prochiral carbonyl compounds to chiral alcohol in Escherichia coli
Lactobacillus brevis alcohol dehydrogenase (Lb-ADH) catalyzes reduction of prochiral carbonyl compounds to chiral alcohol and meanwhile consumes its cofactor NADH into NAD(+), while the cofactor regeneration can be catalyzed by Candida boidinii formate dehydrogenase (Cb-FDH). This work presents thre...
Autores principales: | Li, Bingjuan, Li, Yuxia, Bai, Dongmei, Zhang, Xin, Yang, Huiying, Wang, Jie, Liu, Gang, Yue, Juejie, Ling, Yan, Zhou, Dongsheng, Chen, Huipeng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4208033/ https://www.ncbi.nlm.nih.gov/pubmed/25342633 http://dx.doi.org/10.1038/srep06750 |
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