Cargando…
A thermo-physical analysis of the proton pump vacuolar-ATPase: the constructal approach
Pumping protons across a membrane was a critical step at the origin of life on earth, and it is still performed in all living organisms, including in human cells. Proton pumping is paramount to keep normal cells alive, e.g. for lysosomal digestion and for preparing peptides for immune recognition, b...
Autores principales: | Lucia, Umberto, Ponzetto, Antonio, Deisboeck, Thomas S. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4208057/ https://www.ncbi.nlm.nih.gov/pubmed/25342534 http://dx.doi.org/10.1038/srep06763 |
Ejemplares similares
-
Constructal approach to cell membranes transport: Amending the ‘Norton-Simon’ hypothesis for cancer treatment
por: Lucia, Umberto, et al.
Publicado: (2016) -
Vacuolar-type ATPase: A proton pump to lysosomal trafficking
por: FUTAI, Masamitsu, et al.
Publicado: (2019) -
A Thermodynamic Approach to the Metaboloepigenetics of Cancer
por: Lucia, Umberto, et al.
Publicado: (2023) -
Hyperacidification of Citrus fruits by a vacuolar proton-pumping P-ATPase complex
por: Strazzer, Pamela, et al.
Publicado: (2019) -
Proton pump inhibitors as anti vacuolar-ATPases drugs: a novel anticancer strategy
por: Spugnini, Enrico P, et al.
Publicado: (2010)