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ROS-dependent prostate apoptosis response-4 (Par-4) up-regulation and ceramide generation are the prime signaling events associated with curcumin-induced autophagic cell death in human malignant glioma

Malignant gliomas are extremely resistant to therapies that induce apoptosis, but are less resistant to therapies that induce autophagy. Therefore, drugs targeting autophagy are promising in the management of malignant gliomas. In this study, we investigated the anti-glioma potential of curcumin in...

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Detalles Bibliográficos
Autores principales:	Thayyullathil, Faisal, Rahman, Anees, Pallichankandy, Siraj, Patel, Mahendra, Galadari, Sehamuddin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4208092/ https://www.ncbi.nlm.nih.gov/pubmed/25349781 http://dx.doi.org/10.1016/j.fob.2014.08.005

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