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Optical coherence tomography shows retinal abnormalities associated with optic nerve disease
Optical coherence tomography (OCT) of the macula in patients with primary optic neuropathy has revealed the presence of structural changes in the neurosensory retina in addition to the nerve fibre layer. Subretinal fluid has been documented in papilloedema and non-arteritic ischaemic optic neuropath...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4208346/ https://www.ncbi.nlm.nih.gov/pubmed/24627251 http://dx.doi.org/10.1136/bjophthalmol-2013-304301 |
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author | Tawse, Kirstin L Hedges, Thomas R Gobuty, Marisa Mendoza-Santiesteban, Carlos |
author_facet | Tawse, Kirstin L Hedges, Thomas R Gobuty, Marisa Mendoza-Santiesteban, Carlos |
author_sort | Tawse, Kirstin L |
collection | PubMed |
description | Optical coherence tomography (OCT) of the macula in patients with primary optic neuropathy has revealed the presence of structural changes in the neurosensory retina in addition to the nerve fibre layer. Subretinal fluid has been documented in papilloedema and non-arteritic ischaemic optic neuropathy, and may account for decreased visual acuity in affected patients. Subretinal fluid has also been described from other causes of optic nerve head swelling including diabetic papillopathy and papillitis. Drugs used in the treatment of multiple sclerosis, such as corticosteroids and fingolimod can cause decreased vision due to central serous and cystoid macular oedema sometimes confused with recurrent optic neuritis. A subset of patients with various types of optic atrophy show microcystic changes in the inner nuclear layer on spectral domain OCT imaging. The pathophysiology and visual significance of these retinal changes remain unclear, but may affect the diagnosis and management of optic nerve disorders. |
format | Online Article Text |
id | pubmed-4208346 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | BMJ Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-42083462014-11-05 Optical coherence tomography shows retinal abnormalities associated with optic nerve disease Tawse, Kirstin L Hedges, Thomas R Gobuty, Marisa Mendoza-Santiesteban, Carlos Br J Ophthalmol Supplement Optical coherence tomography (OCT) of the macula in patients with primary optic neuropathy has revealed the presence of structural changes in the neurosensory retina in addition to the nerve fibre layer. Subretinal fluid has been documented in papilloedema and non-arteritic ischaemic optic neuropathy, and may account for decreased visual acuity in affected patients. Subretinal fluid has also been described from other causes of optic nerve head swelling including diabetic papillopathy and papillitis. Drugs used in the treatment of multiple sclerosis, such as corticosteroids and fingolimod can cause decreased vision due to central serous and cystoid macular oedema sometimes confused with recurrent optic neuritis. A subset of patients with various types of optic atrophy show microcystic changes in the inner nuclear layer on spectral domain OCT imaging. The pathophysiology and visual significance of these retinal changes remain unclear, but may affect the diagnosis and management of optic nerve disorders. BMJ Publishing Group 2014-07 2014-03-13 /pmc/articles/PMC4208346/ /pubmed/24627251 http://dx.doi.org/10.1136/bjophthalmol-2013-304301 Text en Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 3.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/3.0/ |
spellingShingle | Supplement Tawse, Kirstin L Hedges, Thomas R Gobuty, Marisa Mendoza-Santiesteban, Carlos Optical coherence tomography shows retinal abnormalities associated with optic nerve disease |
title | Optical coherence tomography shows retinal abnormalities associated with optic nerve disease |
title_full | Optical coherence tomography shows retinal abnormalities associated with optic nerve disease |
title_fullStr | Optical coherence tomography shows retinal abnormalities associated with optic nerve disease |
title_full_unstemmed | Optical coherence tomography shows retinal abnormalities associated with optic nerve disease |
title_short | Optical coherence tomography shows retinal abnormalities associated with optic nerve disease |
title_sort | optical coherence tomography shows retinal abnormalities associated with optic nerve disease |
topic | Supplement |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4208346/ https://www.ncbi.nlm.nih.gov/pubmed/24627251 http://dx.doi.org/10.1136/bjophthalmol-2013-304301 |
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