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How much information can be obtained from tracking the position of the leading edge in a scratch assay?

Moving cell fronts are an essential feature of wound healing, development and disease. The rate at which a cell front moves is driven, in part, by the cell motility, quantified in terms of the cell diffusivity D, and the cell proliferation rate λ. Scratch assays are a commonly reported procedure use...

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Detalles Bibliográficos
Autores principales: Johnston, Stuart T., Simpson, Matthew J., McElwain, D. L. Sean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4208362/
https://www.ncbi.nlm.nih.gov/pubmed/24850906
http://dx.doi.org/10.1098/rsif.2014.0325