Perturbations in small molecule synthesis uncovers an iron-responsive secondary metabolite network in Aspergillus fumigatus

Iron plays a critical role in survival and virulence of the opportunistic pathogen Aspergillus fumigatus. Two transcription factors, the GATA-factor SreA and the bZip-factor HapX oppositely monitor iron homeostasis with HapX activating iron acquisition pathways (e.g., siderophores) and shutting down...

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Detalles Bibliográficos
Autores principales: Wiemann, Philipp, Lechner, Beatrix E., Baccile, Joshua A., Velk, Thomas A., Yin, Wen-Bing, Bok, Jin Woo, Pakala, Suman, Losada, Liliana, Nierman, William C., Schroeder, Frank C., Haas, Hubertus, Keller, Nancy P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4208449/
https://www.ncbi.nlm.nih.gov/pubmed/25386169
http://dx.doi.org/10.3389/fmicb.2014.00530

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4208449/
https://www.ncbi.nlm.nih.gov/pubmed/25386169
http://dx.doi.org/10.3389/fmicb.2014.00530

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