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Resection Leads to Less Recurrence Than Strictureplasty in a Paediatric Population with Obstructive Crohn's Disease

Introduction. Resection and strictureplasty are used to treat patients with obstructive Crohn's disease. Strictureplasty is preferable in adults as it retains bowel length. This study aims to identify differences in outcomes of children undergoing strictureplasty and resection for obstructive C...

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Autores principales: Bamford, Richard, Hay, Ashley, Kumar, Devinder
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4208455/
https://www.ncbi.nlm.nih.gov/pubmed/25374959
http://dx.doi.org/10.1155/2014/709045
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author Bamford, Richard
Hay, Ashley
Kumar, Devinder
author_facet Bamford, Richard
Hay, Ashley
Kumar, Devinder
author_sort Bamford, Richard
collection PubMed
description Introduction. Resection and strictureplasty are used to treat patients with obstructive Crohn's disease. Strictureplasty is preferable in adults as it retains bowel length. This study aims to identify differences in outcomes of children undergoing strictureplasty and resection for obstructive Crohn's disease. Method. Patients under 20 years undergoing surgery over a nine-year period were included. Data was collected on procedures for stenotic Crohn's disease. Patients were divided into 2 groups: Group 1 treated with strictureplasties and Group 2 resections. Postoperative complications and recurrence rates were recorded. Kaplan-Meier method was used to analyze the data. Results. Twenty-six patients and 40 operations were identified. Mean age was 15.6 years (7.2–19.4) with equal numbers of males and females. Mean follow-up was 45.9 months (0.1–149.9). 20/40 procedures involved the terminal ileum; 9/40, the ileocolic junction; 8/40, the upper GI tract; and 3/40, the colon. Group 1 consisted of 19 strictureplasties and Group 2 consisted of 13 resections and 8 combined procedures. Significantly more patients in Group 1 required further surgery (11/19 versus 3/21; P = 0.008). Conclusion. Allowing for variations in disease duration, severity, and previous medical management, these data suggest that resection is preferable to strictureplasty in treating obstructive Crohn's disease in children and adolescents.
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spelling pubmed-42084552014-11-05 Resection Leads to Less Recurrence Than Strictureplasty in a Paediatric Population with Obstructive Crohn's Disease Bamford, Richard Hay, Ashley Kumar, Devinder Surg Res Pract Research Article Introduction. Resection and strictureplasty are used to treat patients with obstructive Crohn's disease. Strictureplasty is preferable in adults as it retains bowel length. This study aims to identify differences in outcomes of children undergoing strictureplasty and resection for obstructive Crohn's disease. Method. Patients under 20 years undergoing surgery over a nine-year period were included. Data was collected on procedures for stenotic Crohn's disease. Patients were divided into 2 groups: Group 1 treated with strictureplasties and Group 2 resections. Postoperative complications and recurrence rates were recorded. Kaplan-Meier method was used to analyze the data. Results. Twenty-six patients and 40 operations were identified. Mean age was 15.6 years (7.2–19.4) with equal numbers of males and females. Mean follow-up was 45.9 months (0.1–149.9). 20/40 procedures involved the terminal ileum; 9/40, the ileocolic junction; 8/40, the upper GI tract; and 3/40, the colon. Group 1 consisted of 19 strictureplasties and Group 2 consisted of 13 resections and 8 combined procedures. Significantly more patients in Group 1 required further surgery (11/19 versus 3/21; P = 0.008). Conclusion. Allowing for variations in disease duration, severity, and previous medical management, these data suggest that resection is preferable to strictureplasty in treating obstructive Crohn's disease in children and adolescents. Hindawi Publishing Corporation 2014 2014-04-01 /pmc/articles/PMC4208455/ /pubmed/25374959 http://dx.doi.org/10.1155/2014/709045 Text en Copyright © 2014 Richard Bamford et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Bamford, Richard
Hay, Ashley
Kumar, Devinder
Resection Leads to Less Recurrence Than Strictureplasty in a Paediatric Population with Obstructive Crohn's Disease
title Resection Leads to Less Recurrence Than Strictureplasty in a Paediatric Population with Obstructive Crohn's Disease
title_full Resection Leads to Less Recurrence Than Strictureplasty in a Paediatric Population with Obstructive Crohn's Disease
title_fullStr Resection Leads to Less Recurrence Than Strictureplasty in a Paediatric Population with Obstructive Crohn's Disease
title_full_unstemmed Resection Leads to Less Recurrence Than Strictureplasty in a Paediatric Population with Obstructive Crohn's Disease
title_short Resection Leads to Less Recurrence Than Strictureplasty in a Paediatric Population with Obstructive Crohn's Disease
title_sort resection leads to less recurrence than strictureplasty in a paediatric population with obstructive crohn's disease
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4208455/
https://www.ncbi.nlm.nih.gov/pubmed/25374959
http://dx.doi.org/10.1155/2014/709045
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