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Impaired Glutathione Redox System Paradoxically Suppresses Angiotensin II-Induced Vascular Remodeling

BACKGROUND: Angiotensin II (AII) plays a central role in vascular remodeling via oxidative stress. However, the interaction between AII and reduced glutathione (GSH) redox status in cardiovascular remodeling remains unknown. METHODS: In vivo: The cuff-induced vascular injury model was applied to Spr...

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Detalles Bibliográficos
Autores principales: Izawa, Kazuma, Okada, Motoi, Sumitomo, Kazuhiro, Nakagawa, Naoki, Aizawa, Yoshiaki, Kawabe, Junichi, Kikuchi, Kenjiro, Hasebe, Naoyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4208744/
https://www.ncbi.nlm.nih.gov/pubmed/25343455
http://dx.doi.org/10.1371/journal.pone.0108115