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Indoxyl Sulfate-Induced Activation of (Pro)renin Receptor Promotes Cell Proliferation and Tissue Factor Expression in Vascular Smooth Muscle Cells

Chronic kidney disease (CKD) is associated with an increased risk of cardiovascular disease (CVD). (Pro)renin receptor (PRR) is activated in the kidney of CKD. The present study aimed to determine the role of indoxyl sulfate (IS), a uremic toxin, in PRR activation in rat aorta and human aortic smoot...

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Detalles Bibliográficos
Autores principales:	Yisireyili, Maimaiti, Saito, Shinichi, Abudureyimu, Shaniya, Adelibieke, Yelixiati, Ng, Hwee-Yeong, Nishijima, Fuyuhiko, Takeshita, Kyosuke, Murohara, Toyoaki, Niwa, Toshimitsu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4208748/ https://www.ncbi.nlm.nih.gov/pubmed/25343458 http://dx.doi.org/10.1371/journal.pone.0109268

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