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Decreased Frequencies of Circulating CD4(+) T Follicular Helper Cells Associated with Diminished Plasma IL-21 in Active Pulmonary Tuberculosis
BACKGROUND: Circulating T follicular helper (Tfh) cells represent a distinct subset of CD4(+) T cells and are important in immunity to infections. Although they have been shown to play a role in experimental models of tuberculosis infection, their role in human tuberculosis remains unexplored. AIMS/...
Autores principales: | Kumar, Nathella Pavan, Sridhar, Rathinam, Hanna, Luke E., Banurekha, Vaithilingam V., Nutman, Thomas B., Babu, Subash |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4208798/ https://www.ncbi.nlm.nih.gov/pubmed/25343703 http://dx.doi.org/10.1371/journal.pone.0111098 |
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