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Ischemia/Reperfusion-Induced CHOP Expression Promotes Apoptosis and Impairs Renal Function Recovery: The Role of Acidosis and GPR4

Endoplasmic reticulum (ER) stress-induced apoptosis is implicated in a wide range of diseases, including ischemia/reperfusion injury (IRI). As a common feature of ER stress, the role of CCAT/enhancer-binding protein homologous protein (CHOP) in renal IRI has not been thoroughly investigated. We foun...

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Detalles Bibliográficos
Autores principales: Dong, Biao, Zhou, Honglan, Han, Conghui, Yao, Jufang, Xu, Longmei, Zhang, Ming, Fu, Yaowen, Xia, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4208823/
https://www.ncbi.nlm.nih.gov/pubmed/25343248
http://dx.doi.org/10.1371/journal.pone.0110944