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Ischemia/Reperfusion-Induced CHOP Expression Promotes Apoptosis and Impairs Renal Function Recovery: The Role of Acidosis and GPR4
Endoplasmic reticulum (ER) stress-induced apoptosis is implicated in a wide range of diseases, including ischemia/reperfusion injury (IRI). As a common feature of ER stress, the role of CCAT/enhancer-binding protein homologous protein (CHOP) in renal IRI has not been thoroughly investigated. We foun...
Autores principales: | Dong, Biao, Zhou, Honglan, Han, Conghui, Yao, Jufang, Xu, Longmei, Zhang, Ming, Fu, Yaowen, Xia, Qiang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4208823/ https://www.ncbi.nlm.nih.gov/pubmed/25343248 http://dx.doi.org/10.1371/journal.pone.0110944 |
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