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Characterization of a weakly expressed KIR2DL1 variant reveals a novel upstream promoter that controls KIR expression
Members of the human KIR class I MHC receptor gene family contain multiple promoters that determine the variegated expression of KIR on NK cells. In order to identify novel genetic alterations associated with decreased KIR expression, a group of donors was characterized for KIR gene content, transcr...
Autores principales: | Wright, Paul W., Li, Hongchuan, Huehn, Andrew, O’Connor, Geraldine M, Cooley, Sarah, Miller, Jeffrey S., Anderson, Stephen K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4208966/ https://www.ncbi.nlm.nih.gov/pubmed/24989671 http://dx.doi.org/10.1038/gene.2014.34 |
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