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Subchondral bone influences chondrogenic differentiation and collagen production of human bone marrow-derived mesenchymal stem cells and articular chondrocytes

INTRODUCTION: Osteoarthritis (OA) is characterized by an imbalance in cartilage and underlying subchondral bone homeostasis. We hypothesized that signals from the subchondral bone may modulate production of matrix components, alter chondrogenic differentiation potential of cocultured bone marrow-der...

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Detalles Bibliográficos
Autores principales:	Leyh, Michaela, Seitz, Andreas, Dürselen, Lutz, Schaumburger, Jens, Ignatius, Anita, Grifka, Joachim, Grässel, Susanne
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4209060/ https://www.ncbi.nlm.nih.gov/pubmed/25296561 http://dx.doi.org/10.1186/s13075-014-0453-9

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