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Healthy diet indicator and mortality in Eastern European populations: prospective evidence from the HAPIEE cohort

BACKGROUND/OBJECTIVES: Unhealthy diet has been proposed as one of the main reasons for the high mortality in Central and Eastern Europe (CEE) and the former Soviet Union (FSU) but individual-level effects of dietary habits on health in the region are sparse. We examined the associations between the...

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Autores principales: Stefler, Denes, Pikhart, Hynek, Jankovic, Nicole, Kubinova, Ruzena, Pajak, Andrzej, Malyutina, Sofia, Simonova, Galina, Feskens, Edith J M, Peasey, Anne, Bobak, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4209172/
https://www.ncbi.nlm.nih.gov/pubmed/25028084
http://dx.doi.org/10.1038/ejcn.2014.134
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author Stefler, Denes
Pikhart, Hynek
Jankovic, Nicole
Kubinova, Ruzena
Pajak, Andrzej
Malyutina, Sofia
Simonova, Galina
Feskens, Edith J M
Peasey, Anne
Bobak, Martin
author_facet Stefler, Denes
Pikhart, Hynek
Jankovic, Nicole
Kubinova, Ruzena
Pajak, Andrzej
Malyutina, Sofia
Simonova, Galina
Feskens, Edith J M
Peasey, Anne
Bobak, Martin
author_sort Stefler, Denes
collection PubMed
description BACKGROUND/OBJECTIVES: Unhealthy diet has been proposed as one of the main reasons for the high mortality in Central and Eastern Europe (CEE) and the former Soviet Union (FSU) but individual-level effects of dietary habits on health in the region are sparse. We examined the associations between the healthy diet indicator (HDI) and all-cause and cause-specific mortality in three CEE/FSU populations. SUBJECTS/METHODS: Dietary intakes of foods and nutrients, assessed by food frequency questionnaire (FFQ) in the Health, Alcohol and Psychosocial Factors in Eastern Europe (HAPIEE) cohort study, were used to construct the HDI which follows the WHO 2003 dietary recommendations. Among 18 559 eligible adult participants (age range: 45-69 years) without history of major chronic diseases at baseline, 1 209 deaths occurred over mean follow up of 7 years. The association between HDI and mortality was estimated by Cox regression. RESULTS: After adjusting for covariates, HDI was inversely and statistically significantly associated with cardiovascular disease (CVD) and coronary heart disease (CHD) mortality, but not with other cause-specific and all-cause mortality in the pooled sample. Hazard ratios per one standard deviation (SD) increase in HDI score were 0.95 (95%CI 0.89-1.00, p=0.068), 0.90 (0.81-0.99, p=0.030) and 0.85 (0.74-0.97, p=0.018) for all-cause, CVD and CHD mortality, respectively. Population attributable risk fractions for low HDI were 2.9% for all-cause, 14.2% for CVD and 10.7% for CHD mortality. CONCLUSIONS: These findings support the hypothesis that unhealthy diet has played a role in the high CVD mortality in Eastern Europe.
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spelling pubmed-42091722015-06-01 Healthy diet indicator and mortality in Eastern European populations: prospective evidence from the HAPIEE cohort Stefler, Denes Pikhart, Hynek Jankovic, Nicole Kubinova, Ruzena Pajak, Andrzej Malyutina, Sofia Simonova, Galina Feskens, Edith J M Peasey, Anne Bobak, Martin Eur J Clin Nutr Article BACKGROUND/OBJECTIVES: Unhealthy diet has been proposed as one of the main reasons for the high mortality in Central and Eastern Europe (CEE) and the former Soviet Union (FSU) but individual-level effects of dietary habits on health in the region are sparse. We examined the associations between the healthy diet indicator (HDI) and all-cause and cause-specific mortality in three CEE/FSU populations. SUBJECTS/METHODS: Dietary intakes of foods and nutrients, assessed by food frequency questionnaire (FFQ) in the Health, Alcohol and Psychosocial Factors in Eastern Europe (HAPIEE) cohort study, were used to construct the HDI which follows the WHO 2003 dietary recommendations. Among 18 559 eligible adult participants (age range: 45-69 years) without history of major chronic diseases at baseline, 1 209 deaths occurred over mean follow up of 7 years. The association between HDI and mortality was estimated by Cox regression. RESULTS: After adjusting for covariates, HDI was inversely and statistically significantly associated with cardiovascular disease (CVD) and coronary heart disease (CHD) mortality, but not with other cause-specific and all-cause mortality in the pooled sample. Hazard ratios per one standard deviation (SD) increase in HDI score were 0.95 (95%CI 0.89-1.00, p=0.068), 0.90 (0.81-0.99, p=0.030) and 0.85 (0.74-0.97, p=0.018) for all-cause, CVD and CHD mortality, respectively. Population attributable risk fractions for low HDI were 2.9% for all-cause, 14.2% for CVD and 10.7% for CHD mortality. CONCLUSIONS: These findings support the hypothesis that unhealthy diet has played a role in the high CVD mortality in Eastern Europe. 2014-07-16 2014-12 /pmc/articles/PMC4209172/ /pubmed/25028084 http://dx.doi.org/10.1038/ejcn.2014.134 Text en Users may view, print, copy, and download text and data-mine the content in such documents, for the purposes of academic research, subject always to the full Conditions of use:http://www.nature.com/authors/editorial_policies/license.html#terms
spellingShingle Article
Stefler, Denes
Pikhart, Hynek
Jankovic, Nicole
Kubinova, Ruzena
Pajak, Andrzej
Malyutina, Sofia
Simonova, Galina
Feskens, Edith J M
Peasey, Anne
Bobak, Martin
Healthy diet indicator and mortality in Eastern European populations: prospective evidence from the HAPIEE cohort
title Healthy diet indicator and mortality in Eastern European populations: prospective evidence from the HAPIEE cohort
title_full Healthy diet indicator and mortality in Eastern European populations: prospective evidence from the HAPIEE cohort
title_fullStr Healthy diet indicator and mortality in Eastern European populations: prospective evidence from the HAPIEE cohort
title_full_unstemmed Healthy diet indicator and mortality in Eastern European populations: prospective evidence from the HAPIEE cohort
title_short Healthy diet indicator and mortality in Eastern European populations: prospective evidence from the HAPIEE cohort
title_sort healthy diet indicator and mortality in eastern european populations: prospective evidence from the hapiee cohort
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4209172/
https://www.ncbi.nlm.nih.gov/pubmed/25028084
http://dx.doi.org/10.1038/ejcn.2014.134
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