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12-hydroxyeicosatetraenoic acid is associated with variability in aspirin-induced platelet inhibition
BACKGROUND: Aspirin is one of the most widely used non-steroidal anti-inflammatory drugs (NSAIDs). It is also a commonly used anti-platelet drug, which inhibits the formation of the platelet activator, thromboxane A(2) (TxA(2)) via inhibition of cyclooxygenase-1 (COX-1). However, the presence of a p...
Autores principales: | Maskrey, Benjamin H, Rushworth, Gordon F, Law, Matthew H, Treweeke, Andrew T, Wei, Jun, Leslie, Stephen J, Megson, Ian L, Whitfield, Phillip D |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4209229/ https://www.ncbi.nlm.nih.gov/pubmed/25349537 http://dx.doi.org/10.1186/s12950-014-0033-4 |
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