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12-hydroxyeicosatetraenoic acid is associated with variability in aspirin-induced platelet inhibition

BACKGROUND: Aspirin is one of the most widely used non-steroidal anti-inflammatory drugs (NSAIDs). It is also a commonly used anti-platelet drug, which inhibits the formation of the platelet activator, thromboxane A(2) (TxA(2)) via inhibition of cyclooxygenase-1 (COX-1). However, the presence of a p...

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Detalles Bibliográficos
Autores principales:	Maskrey, Benjamin H, Rushworth, Gordon F, Law, Matthew H, Treweeke, Andrew T, Wei, Jun, Leslie, Stephen J, Megson, Ian L, Whitfield, Phillip D
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4209229/ https://www.ncbi.nlm.nih.gov/pubmed/25349537 http://dx.doi.org/10.1186/s12950-014-0033-4

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