Successful Treatment of Two Cases of Squamous Cell Carcinoma on the Ear with Intra-Arterial Administration of Peplomycin through a Superficial Temporal Artery

Cutaneous squamous cell carcinoma (SCC) is the second most common non-melanoma skin cancer and tends to develop in sun-exposed cosmetic areas, including the ear. In this report, we describe two cases of SCC on the ear successfully treated with intra-arterial administration of peplomycin through a su...

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Autores principales: Haga, Takahiro, Fujimura, Taku, Takeuchi, Izuho, Deguchi, Masatoshi, Aiba, Setsuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2014
Materias:
Published online: September, 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4209265/
https://www.ncbi.nlm.nih.gov/pubmed/25408647
http://dx.doi.org/10.1159/000367804
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author Haga, Takahiro
Fujimura, Taku
Takeuchi, Izuho
Deguchi, Masatoshi
Aiba, Setsuya
author_facet Haga, Takahiro
Fujimura, Taku
Takeuchi, Izuho
Deguchi, Masatoshi
Aiba, Setsuya
author_sort Haga, Takahiro
collection PubMed
description Cutaneous squamous cell carcinoma (SCC) is the second most common non-melanoma skin cancer and tends to develop in sun-exposed cosmetic areas, including the ear. In this report, we describe two cases of SCC on the ear successfully treated with intra-arterial administration of peplomycin through a superficial temporal artery. In addition to this selective chemotherapy, we administered oral tegafur, which achieved complete remission of the tumor. These findings suggest that intra-arterial administration of peplomycin with tegafur is one of the optimal therapies for the treatment of SCC developing on the ear.
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spelling pubmed-42092652014-11-18 Successful Treatment of Two Cases of Squamous Cell Carcinoma on the Ear with Intra-Arterial Administration of Peplomycin through a Superficial Temporal Artery Haga, Takahiro Fujimura, Taku Takeuchi, Izuho Deguchi, Masatoshi Aiba, Setsuya Case Rep Dermatol Published online: September, 2014 Cutaneous squamous cell carcinoma (SCC) is the second most common non-melanoma skin cancer and tends to develop in sun-exposed cosmetic areas, including the ear. In this report, we describe two cases of SCC on the ear successfully treated with intra-arterial administration of peplomycin through a superficial temporal artery. In addition to this selective chemotherapy, we administered oral tegafur, which achieved complete remission of the tumor. These findings suggest that intra-arterial administration of peplomycin with tegafur is one of the optimal therapies for the treatment of SCC developing on the ear. S. Karger AG 2014-09-04 /pmc/articles/PMC4209265/ /pubmed/25408647 http://dx.doi.org/10.1159/000367804 Text en Copyright © 2014 by S. Karger AG, Basel http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article licensed under the terms of the Creative Commons Attribution-NonCommercial 3.0 Unported license (CC BY-NC) (www.karger.com/OA-license), applicable to the online version of the article only. Users may download, print and share this work on the Internet for noncommercial purposes only, provided the original work is properly cited, and a link to the original work on http://www.karger.com and the terms of this license are included in any shared versions.
spellingShingle Published online: September, 2014
Haga, Takahiro
Fujimura, Taku
Takeuchi, Izuho
Deguchi, Masatoshi
Aiba, Setsuya
Successful Treatment of Two Cases of Squamous Cell Carcinoma on the Ear with Intra-Arterial Administration of Peplomycin through a Superficial Temporal Artery
title Successful Treatment of Two Cases of Squamous Cell Carcinoma on the Ear with Intra-Arterial Administration of Peplomycin through a Superficial Temporal Artery
title_full Successful Treatment of Two Cases of Squamous Cell Carcinoma on the Ear with Intra-Arterial Administration of Peplomycin through a Superficial Temporal Artery
title_fullStr Successful Treatment of Two Cases of Squamous Cell Carcinoma on the Ear with Intra-Arterial Administration of Peplomycin through a Superficial Temporal Artery
title_full_unstemmed Successful Treatment of Two Cases of Squamous Cell Carcinoma on the Ear with Intra-Arterial Administration of Peplomycin through a Superficial Temporal Artery
title_short Successful Treatment of Two Cases of Squamous Cell Carcinoma on the Ear with Intra-Arterial Administration of Peplomycin through a Superficial Temporal Artery
title_sort successful treatment of two cases of squamous cell carcinoma on the ear with intra-arterial administration of peplomycin through a superficial temporal artery
topic Published online: September, 2014
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4209265/
https://www.ncbi.nlm.nih.gov/pubmed/25408647
http://dx.doi.org/10.1159/000367804
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