Telomere dysfunction suppresses multiple endocrine neoplasia in mice

Multiple endocrine neoplasia (MEN) syndrome is typified by the occurrence of tumors in two or more hormonal tissues. Whereas the genetics of MEN syndrome is relatively well understood, the tumorigenic mechanisms for these cancers remain relatively obscure. The Cdk4(R24C) mouse model develops highly...

Descripción completa

Detalles Bibliográficos
Autores principales: Lee, Ji-Hyeon, Anver, Miriam, Kost-Alimova, Maria, Protopopov, Alexei, DePinho, Ronald A., Rane, Sushil G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4209601/
https://www.ncbi.nlm.nih.gov/pubmed/25352948

Ejemplares similares

Ejemplares similares