Six-Digit CPK and Mildly Affected Renal Function in McArdle Disease

A previously healthy, white 12-year-old girl presented with diffuse body aches and poor perfusion. She developed severe respiratory failure and marked rhabdomyolysis and was mechanically ventilated. Although her CPK peaked at 500,000 IU/L, her renal function was mildly affected and her creatinine di...

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Detalles Bibliográficos
Autores principales: Spyropoulos, George, Kratimenos, Panagiotis, Mcinnes, Andrew D., DeGroote, Richard J., Koutroulis, Ioannis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4209763/
https://www.ncbi.nlm.nih.gov/pubmed/25371840
http://dx.doi.org/10.1155/2014/704398
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author Spyropoulos, George
Kratimenos, Panagiotis
Mcinnes, Andrew D.
DeGroote, Richard J.
Koutroulis, Ioannis
author_facet Spyropoulos, George
Kratimenos, Panagiotis
Mcinnes, Andrew D.
DeGroote, Richard J.
Koutroulis, Ioannis
author_sort Spyropoulos, George
collection PubMed
description A previously healthy, white 12-year-old girl presented with diffuse body aches and poor perfusion. She developed severe respiratory failure and marked rhabdomyolysis and was mechanically ventilated. Although her CPK peaked at 500,000 IU/L, her renal function was mildly affected and her creatinine did not exceed the 0.8 mg/dL. The rhabdomyolysis was gradually resolved following aggressive fluid hydration. The patient did not require dialysis and made a complete recovery. Genetic studies revealed the diagnosis of McArdle disease.
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spelling pubmed-42097632014-11-04 Six-Digit CPK and Mildly Affected Renal Function in McArdle Disease Spyropoulos, George Kratimenos, Panagiotis Mcinnes, Andrew D. DeGroote, Richard J. Koutroulis, Ioannis Case Rep Pediatr Case Report A previously healthy, white 12-year-old girl presented with diffuse body aches and poor perfusion. She developed severe respiratory failure and marked rhabdomyolysis and was mechanically ventilated. Although her CPK peaked at 500,000 IU/L, her renal function was mildly affected and her creatinine did not exceed the 0.8 mg/dL. The rhabdomyolysis was gradually resolved following aggressive fluid hydration. The patient did not require dialysis and made a complete recovery. Genetic studies revealed the diagnosis of McArdle disease. Hindawi Publishing Corporation 2014 2014-10-09 /pmc/articles/PMC4209763/ /pubmed/25371840 http://dx.doi.org/10.1155/2014/704398 Text en Copyright © 2014 George Spyropoulos et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Spyropoulos, George
Kratimenos, Panagiotis
Mcinnes, Andrew D.
DeGroote, Richard J.
Koutroulis, Ioannis
Six-Digit CPK and Mildly Affected Renal Function in McArdle Disease
title Six-Digit CPK and Mildly Affected Renal Function in McArdle Disease
title_full Six-Digit CPK and Mildly Affected Renal Function in McArdle Disease
title_fullStr Six-Digit CPK and Mildly Affected Renal Function in McArdle Disease
title_full_unstemmed Six-Digit CPK and Mildly Affected Renal Function in McArdle Disease
title_short Six-Digit CPK and Mildly Affected Renal Function in McArdle Disease
title_sort six-digit cpk and mildly affected renal function in mcardle disease
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4209763/
https://www.ncbi.nlm.nih.gov/pubmed/25371840
http://dx.doi.org/10.1155/2014/704398
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