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Targeting DNGR-1 (CLEC9A) with antibody/MUC1 peptide conjugates as a vaccine for carcinomas
DCs are the most potent APCs and are the focus of many immunotherapeutic approaches for the treatment of cancer, although most of these approaches require the ex vivo generation and pulsing of DCs. We have targeted a subset of DCs in vivo using an Ab to DNGR-1, a C-type lectin dedicated to the cross...
Autores principales: | Picco, Gianfranco, Beatson, Richard, Taylor-Papadimitriou, Joyce, Burchell, Joy M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BlackWell Publishing Ltd
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4209794/ https://www.ncbi.nlm.nih.gov/pubmed/24648154 http://dx.doi.org/10.1002/eji.201344076 |
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