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Alternative splice variants of AID are not stoichiometrically present at the protein level in chronic lymphocytic leukemia

Activation-induced deaminase (AID) is a DNA-mutating enzyme that mediates class-switch recombination as well as somatic hypermutation of antibody genes in B cells. Due to off-target activity, AID is implicated in lymphoma development by introducing genome-wide DNA damage and initiating chromosomal t...

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Detalles Bibliográficos
Autores principales:	Rebhandl, Stefan, Huemer, Michael, Zaborsky, Nadja, Gassner, Franz Josef, Catakovic, Kemal, Felder, Thomas Klaus, Greil, Richard, Geisberger, Roland
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BlackWell Publishing Ltd 2014
Materias:	Clinical Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4209801/ https://www.ncbi.nlm.nih.gov/pubmed/24668151 http://dx.doi.org/10.1002/eji.201343853

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