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Metabolism via Arginase or Nitric Oxide Synthase: Two Competing Arginine Pathways in Macrophages

Macrophages play a major role in the immune system, both as antimicrobial effector cells and as immunoregulatory cells, which induce, suppress or modulate adaptive immune responses. These key aspects of macrophage biology are fundamentally driven by the phenotype of macrophage arginine metabolism th...

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Detalles Bibliográficos
Autores principales: Rath, Meera, Müller, Ingrid, Kropf, Pascale, Closs, Ellen I., Munder, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4209874/
https://www.ncbi.nlm.nih.gov/pubmed/25386178
http://dx.doi.org/10.3389/fimmu.2014.00532