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Regioselective Chemoenzymatic Synthesis of Ganglioside Disialyl Tetrasaccharide Epitopes
[Image: see text] A novel chemoenzymatic approach for the synthesis of disialyl tetrasaccharide epitopes found as the terminal oligosaccharides of GD1α, GT1aα, and GQ1bα is described. It relies on chemical manipulation of enzymatically generated trisaccharides as conformationally constrained accepto...
Autores principales: | Meng, Xin, Yao, Wenlong, Cheng, Jiansong, Zhang, Xu, Jin, Lan, Yu, Hai, Chen, Xi, Wang, Fengshan, Cao, Hongzhi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2014
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4210053/ https://www.ncbi.nlm.nih.gov/pubmed/24649890 http://dx.doi.org/10.1021/ja5000609 |
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