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Dynamic Kinetic Asymmetric Cross-Benzoin Additions of β-Stereogenic α-Keto Esters

[Image: see text] The dynamic kinetic resolution of β-halo α-keto esters via an asymmetric cross-benzoin reaction is described. A chiral N-heterocyclic carbene catalyzes the umpolung addition of aldehydes to racemic α-keto esters. The resulting fully substituted β-halo glycolic ester products are ob...

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Detalles Bibliográficos
Autores principales:	Goodman, C. Guy, Johnson, Jeffrey S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2014
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4210110/ https://www.ncbi.nlm.nih.gov/pubmed/25299730 http://dx.doi.org/10.1021/ja508521a

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