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Comparative Analysis and Modeling of the Severity of Steatohepatitis in DDC-Treated Mouse Strains

BACKGROUND: Non-alcoholic fatty liver disease (NAFLD) has a broad spectrum of disease states ranging from mild steatosis characterized by an abnormal retention of lipids within liver cells to steatohepatitis (NASH) showing fat accumulation, inflammation, ballooning and degradation of hepatocytes, an...

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Detalles Bibliográficos
Autores principales:	Pandey, Vikash, Sultan, Marc, Kashofer, Karl, Ralser, Meryem, Amstislavskiy, Vyacheslav, Starmann, Julia, Osprian, Ingrid, Grimm, Christina, Hache, Hendrik, Yaspo, Marie-Laure, Sültmann, Holger, Trauner, Michael, Denk, Helmut, Zatloukal, Kurt, Lehrach, Hans, Wierling, Christoph
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4210132/ https://www.ncbi.nlm.nih.gov/pubmed/25347188 http://dx.doi.org/10.1371/journal.pone.0111006

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