A Comparison of Three Electrophysiological Methods for the Assessment of Disease Status in a Mild Spinal Muscular Atrophy Mouse Model

OBJECTIVES: There is a need for better, noninvasive quantitative biomarkers for assessing the rate of progression and possible response to therapy in spinal muscular atrophy (SMA). In this study, we compared three electrophysiological measures: compound muscle action potential (CMAP) amplitude, moto...

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Detalles Bibliográficos
Autores principales: Li, Jia, Geisbush, Tom R., Arnold, William D., Rosen, Glenn D., Zaworski, Phillip G., Rutkove, Seward B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4210182/
https://www.ncbi.nlm.nih.gov/pubmed/25347197
http://dx.doi.org/10.1371/journal.pone.0111428

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