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Down Regulation of Wnt Signaling Mitigates Hypoxia-Induced Chemoresistance in Human Osteosarcoma Cells

Osteosarcoma (OS) is the most common type of solid bone cancer and remains the second leading cause of cancer-related death for children and young adults. Hypoxia is an element intrinsic to most solid-tumor microenvironments, including that of OS, and is associated with resistance to therapy, poor s...

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Detalles Bibliográficos
Autores principales:	Scholten, Donald J., Timmer, Christine M., Peacock, Jacqueline D., Pelle, Dominic W., Williams, Bart O., Steensma, Matthew R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4210185/ https://www.ncbi.nlm.nih.gov/pubmed/25347326 http://dx.doi.org/10.1371/journal.pone.0111431

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