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Rat N-ERC/Mesothelin as a Marker for In Vivo Screening of Drugs against Pancreas Cancer
Pancreatic ductal adenocarcinoma (PDA) is a highly lethal disease, which is usually diagnosed in an advanced stage. We have established transgenic rats carrying a mutated K-ras gene controlled by Cre/loxP activation. The animals develop PDA which is histopathologically similar to that in humans. Pre...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4210215/ https://www.ncbi.nlm.nih.gov/pubmed/25347530 http://dx.doi.org/10.1371/journal.pone.0111481 |